Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate

Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate

Application

Phe-Arg -naphthylamide dihydrochloride has been used to evaluate the contribution of efflux pumps to antimicrobial resistance. It has also been used for minimal inhibitory concentration testing in the presence of an efflux pump inhibitor.

General description

Phe-Arg ?-naphthylamide, a peptidomimetic compound, is an efflux pump inhibitor (EPI). It acts on the major multidrug resistance efflux transporters of Gram-negative bacteria. Phe-Arg -naphthylamide lowers fluoroquinolone resistance in Pseudomonas aeruginosa.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

Substrate for dipeptidyl aminopeptidase I (cathepsin C).

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Code Description Quality Level InChI key InChI Manufacturer Storage Temp. Solubility Form Assay Price Quantity
3578664 Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate 200 ZMTAZQYLEGNUTJ-UHFFFAOYSA-N 1S/C25H30N6O2.ClH/c26-21(15-17-7-2-1-3-8-17)23(32)31-22(11-6-14-29-25(27)28)24(33)30-20-13-12-18-9-4-5-10-19(18)16-20;/h1-5,7-10,12-13,16,21-22H,6,11,14-15,26H SIGMA-ALDRICH
£948.54 (exc VAT) per 250MG
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3578665 Phe-Arg beta-naphthylamide dihydrochloride, cathepsin substrate 200 ZMTAZQYLEGNUTJ-UHFFFAOYSA-N 1S/C25H30N6O2.ClH/c26-21(15-17-7-2-1-3-8-17)23(32)31-22(11-6-14-29-25(27)28)24(33)30-20-13-12-18-9-4-5-10-19(18)16-20;/h1-5,7-10,12-13,16,21-22H,6,11,14-15,26H SIGMA-ALDRICH
£181.07 (exc VAT) per 25MG
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