Cytosine beta-D-arabinofuranoside hydrochloride, crystalline

Descriptions

Application

Cytosine ?-D-arabinofuranoside hydrochloride has been used in fetal bovine serum supplemented Dulbecco?s modified eagle medium (FBS-DMEM) and B27/neurobasal-A medium to inhibit the growth of glial cells. It has also been used to inhibit astrocyte proliferation in embryonic spinal cord neurons.

Biochem/physiol Actions

Ara-C is phosphorylated to Ara-CTP and is incorporatee into DNA. It inhibits DNA replication by forming cleavage complexes with topoisomerase I resulting in DNA fragmentation, and ultimately induces apoptosis via the PKC signaling pathway. Does not inhibit RNA synthesis. Anti-leukemia agent.

Packaging

100, 500 mg in glass bottle

1, 5 g in glass bottle

25 mg in poly bottle

Specifications

No detailed specifications are available for this product.

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Code	Description	Quality Level	mp	InChI key	InChI	Manufacturer	Storage Temp.	Form	Price	Quantity
3577680	Cytosine beta-D-arabinofuranoside hydrochloride, crystalline	200	197-198 °C (lit.)	KCURWTAZOZXKSJ-JBMRGDGGSA-N	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1	SIGMA-ALDRICH	2-8°C	crystalline	£85.80 (exc VAT) per 100MG	- +
3577681	Cytosine beta-D-arabinofuranoside hydrochloride, crystalline	200	197-198 °C (lit.)	KCURWTAZOZXKSJ-JBMRGDGGSA-N	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1	SIGMA-ALDRICH	2-8°C	crystalline	£469.39 (exc VAT) per 1G	- +
3577682	Cytosine beta-D-arabinofuranoside hydrochloride, crystalline	200	197-198 °C (lit.)	KCURWTAZOZXKSJ-JBMRGDGGSA-N	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1	SIGMA-ALDRICH	2-8°C	crystalline	£60.87 (exc VAT) per 25MG	- +
3577683	Cytosine beta-D-arabinofuranoside hydrochloride, crystalline	200	197-198 °C (lit.)	KCURWTAZOZXKSJ-JBMRGDGGSA-N	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1	SIGMA-ALDRICH	2-8°C	crystalline	£288.32 (exc VAT) per 500MG	- +
3577684	Cytosine beta-D-arabinofuranoside hydrochloride, crystalline	200	197-198 °C (lit.)	KCURWTAZOZXKSJ-JBMRGDGGSA-N	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1	SIGMA-ALDRICH	2-8°C	crystalline	Click Add to Quote for price and delivery	- +